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Importantly, overexpression of keap1a or knockdown of hmox1a partially rescued the blood clot formation, suggesting that the disrupted Keap1-Nrf2 signaling is responsible for the venous thrombosis-like phenotypes in smarca5 mutants

The daily intake of EGCG (epigallocatechin-3-gallate) should not reach or exceed 800 mg per day

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