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There is also formal clinical investigation, including the cystic fibrosis trial noted earlier

JTCVS Open 25:424-434, 2025

It has been reported that SCFAs, chiefly butyrate, possess a neuroprotective effect, they promote anti-inflammatory pathways and enhance mitochondrial function in neuronal cells (123)

The decrease in activity causes fewer amounts of hormones and peptides to be produced by the thymus

However, exploratory analyzes revealed it could significantly slow the progression of motor symptoms, an effect particularly pronounced in rapid-progressor subgroups, for example, users of monoamine oxidase B inhibitors, patients with diffuse malignant phenotypes [208]

10.1021/acsabm.0c01438 36 ChenT.LiL.XuG.WangX.WangJ.ChenY.et al (2018)