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From this synthesis, we propose restoration of copper balance using copper delivery agents in combination with chaperones/chaperone mimetics, perhaps in conjunction with the neuroprotective amino acid serine, as a promising strategy in the treatment of this incurable disease

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The safety and potential side effects of using biomolecules for SGN protection and differentiation are also concerns, with long-term effects and side effects still poorly understood

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Glycine Levels are Increased in Response to GlyNAC Independently of GSH Status An important observation of this study is the lower levels of glycine in healthy older adults (by approximately 15.5% in plasma and 8.9% in whole blood) compared to young subjects (Table 1)