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Prenatal vitamin B12 status and cognitive functioning in children at 4 years of age: The ECLIPSES Study. Maternal & Child Nutrition 20.1 (2024): e13580.

22 The causes of aphthous ulcers are unknown, and may include systemic diseases, nutritional deficiencies, food allergies, genetic predisposition, immune disorders, medications and human immunodeficiency virus infection

Free B12 then binds to R-proteins secreted by salivary glands

NNMT uses up nicotinamide by tagging it with a methyl group (a process called methylation) and sending it out as waste

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