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A study by James Fell and Robert Voas refutes this claim [5]
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Melanocortin peptides and their receptors: new targets for anti-inflammatory therapy
59 Prospective studies on this topic have focused mainly on normalising serum B 12 concentrations and should be interpreted with caution since the specific goal of treatment in symptomatic B 12 deficiency is alleviating symptoms
Headache: The most commonly reported adverse event was headache, characterized as mild to moderate in severity
