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Importantly, in mouse xenograft models, 6p produced robust antitumor activity against NSCLC and melanoma, indicating its promise as a selective and effective FASN-targeted cancer therapy for future research and trials (260)

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282, 1715717165.10.1074/jbc.M700804200 20 HibiT.NiiH.NakatsuT.KimuraA.KatoH.HiratakeJ.OdaJ

This is important during atopic dermatitis therapy because their stimulation increases the production of B, T, and NK lymphocytes, which leads to the restoration of balance between T lymphocytes and consequently alleviates the symptoms of atopic dermatitis, including excessive keratinization and lichenification resulting from intense itching

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