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Description
With the Warburg effect, he described the metabolic shift in cancer cells from oxidative phosphorylation to an increased rate of aerobic glycolysis, to produce significantly higher amounts of ATP [46]
doi: 10.1038/s41574-021-00593-z
Biomedicine 6 (1), 28
And so that has been challenging
Chem Biol Interact 31, 30111
GSTP1 conjugates and detoxifies ethacrynic acid (Ahokas et al, 1984), which was significantly more toxic to GSTP1 null cells (1.3-fold increase in IC 50 , P =0.004, Figure 2A)
