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The exact mechanisms of IIM pathogenesis remain unknown, but it is widely believed to result from the interplay of genetic, environmental, immune, and non-immune factors (endoplasmic reticulum stress, oxidative stress, abnormal autophagy regulation, hypoxia, and angiogenesis) [221]
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CF: bibliographic search, revision of the text
2011 Sep;17(9):827-33
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[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Bekker A, Holland HD, Wang PL, Rumble D, Iii, Stein HJ, Hannah JL, Coetzee LL, Beukes NJ
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Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology
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Actuators, B 2011, 160 (1), 1444-1449.