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Graphic representation was achieved using the MS Excel program, with the following functions: Pivot Tables, Functions, Statistical, Chart, and Data

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Copper transport: Copper is an essential cofactor for lysyl oxidase (collagen cross-linking) and several antioxidant enzymes

J Virol 89(4):19541964 Denison MR, Graham RL, Donaldson EF, Eckerle LD, Baric RS (2011) Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity

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While various studies have focused on the beneficial effects of prebiotics, probiotics, and synbiotics individually, few studies have been published on the combined effects of prebiotics and probiotics