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Proteomic analysis was performed to identify differentially expressed proteins (DEPs), while metabolomic profiling was used to characterize metabolic changes
These results suggest that both exogenous and endogenous HNE can inhibit NLRP3 inflammasome activation

The larger trial didnt hold up well enough for pharmaceutical development to continue

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Yang Y, Zhang Y, Liu X, Zuo J, Wang K, Liu W, Ge J
