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described two deaths due to VPA intoxication in their retrospective study of 316 patients in Iran ( Discussion In the case we present here, the assumed amount of ingested VPA was 56 g, which is, compared with other cases, at the upper end of the dose range in the reported cases

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Complementary clinical and meta-analytic data consistently demonstrate systemic redox imbalance, including lower glutathione reserves, altered GSH/GSSG ratios, increased lipid peroxidation, and dysregulated NRF2 signaling, linking oxidative status to immune activation and synaptic dysfunction (James et al., 2004

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