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Variants in genes responsible for dopamine metabolism, synaptic function, and neuroinflammation have been identified as risk factors for Parkinson's disease

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Over the treatment period, body weight loss in cachectic Apc(Min/+) mice receiving vehicle (Apc(Min/+)V) was significantly greater (14% 2.3) than in all other groups, including the quercetin-treated Apc(Min/+) mice (Apc(Min/+)Q), which lost significantly less weight (9% 1.3)

[Abstract] University of Gothenburg

Furthermore, in the RAS WT subgroup, the ORR (PRc) was 50.0%, the DCR was 83.3%, the median PFS was 6.3 months, and the median OS was not reached (Saeed et al., 2022)