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doi: 10.1016/s0014-5793(03)01077-9

This is, in fact, exactly what the 5-on/2-off schedule already builds in

Mixed centrally and peripherally acting anti-obesity medicines with evidence for use in older adults Three GLP-1 receptor agonists are currently approved for obesity pharmacotherapy (Tirzepatide is a dual GIP-GLP-1 receptor agonist)

I racked up diagnoses and illnesses and was prescribed endless amounts of medications