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Battaglia G, et al

[1] Patients with diabetes and pre-existing retinopathy should be monitored for worsening retinopathy during rapid improvement in glycemic control

Quantitative determination of hydroquinone in skin-lightening cosmetic samples The concentration of hydroquinone in each cosmetic sample was determined using a validated UV-spectrophotometric method at a wavelength of 290 nm

Whether oral use is appropriate depends on the patients symptoms, product quality, treatment goal, and provider recommendation

H.JacquesP.SelhubJ.DoughertyL.ColditzG

Supplementary material The Supplementary Material for this article can be found online at: Abbreviations AQ amodiaquine AQ-SG 5-glutathion- S -yl-amodiaquine AQ-QI amodiaquine-quinoneimine BSO L -buthionine-sulfoximine CDNB 1-chloro-2, 4-dinitrobenzene CYP cytochromes P450 DEAQ N -desethylamodiaquine DEAQ-SG 5-glutathion- S -yl- N -desethylamodiaquine DEAQ-QI N -desethylamodiaquine-quinoneimine DMEM Dulbeccos modified Eagle medium DMF N,N -dimethylformamide ER endoplasmic reticulum FBS fetal bovine serum GSH glutathione GSSG glutathione disulfide GST glutathione S -transferase H 2 O 2 hydrogen peroxide HClO 4 perchloric acid HRP horseradish peroxidase NQO1 NAD(P)H:quinone oxidoreductase 1 NAPQI N -acetyl- p -benzoquinonimine PBS phosphate-buffered saline QI quinoneimine