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This is consistent with a recent report that salvianolic acid A results in a dramatic activation of the Akt/mTOR signalling, followed by activation of the Nrf2/HO-1 axis in retinal pigment epithelia cells 60

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Rubino D, Abrahamsson N, Davies M, Hesse D, Greenway FL, Jensen C, et al

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Supplementation of GH in culture medium without serum (avoiding an exogenous source of IGF-1) induced chondrocyte proliferation, suggesting direct effects of GH on chondrocytes [131]

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