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Pediatric use The safety of this product in premature infants, newborns, infants, toddlers or children has not been established due to insufficient clinical data

doi: 10.1186/1745-6215-15-115

Several linear (Manier et al., 2020) and non-linear strategies (QC-Robust Smoothing Splines (QC-RSC) (Kirwan et al., 2013), QC-Support vector regression correction (QC-SVRC)) (Moreno-Torres et al., 2021) have been proposed for the modeling of within-batch effects

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Minor side effects may include: Gastrointestinal discomfort Headache Skin rash (rare) Serious adverse reactions are extremely rare but should prompt immediate medical consultation

Dosage should be individualized for maximum beneficial effect