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"Active Folate Versus Folic Acid: The Role of 5-MTHF (Methylfolate) in Human Health"

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In the hippocampus, A can induce the activation of COX-2 and Bax, and inhibit Bcl-2, cAMP response element binding protein (CREB), BDNF, and TrkB, while naringin can attenuate these effects of A (Choi et al., 2023)

1c,d) which catabolize 25(OH)VD 3 and active 1,25(OH) 2 D 3