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In these models, we take into account the reaction geometry of common thiol-disulfide exchange reactions and distinguish hypothetical protein areas that might either interact with the disulfide substrate (a scaffold site) or the reducing agent (an activator site) (Fig

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Also a significant correlation was found between GPX and ALT level

Nrf2 regulates key components of anti-ferroptotic pathways, positioning it as a central modulator of lipid peroxidation and ferroptosis (62)

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Any disruption in this balance is referred to as oxidative stress, which may result from various disorders or dysfunctions in normal physiological systems