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Moreover, NAMPT activity is crucial for the beneficial effects of calorie restriction, including improved oxidative stress management, mitochondrial biogenesis, and metabolic adaptation, as reported in a study involving Sprague-Dawley rats 213

Keywords: obesity, glucagon, GLP-1, GIP, dual-agonist therapies, triple agonist therapies Obesity Obesity is a complex, chronic, miscellaneous disease marked by excessive fat accumulation that significantly impacts health with an alarming rise in global prevalence, affecting over 890 million adults by the year 2022

When the cancer cells break out of latency, they reinitiate overt outgrowth and overtake the local tissue microenvironment

Vigorous exercise, especially in high temperatures, often causes muscle cramps

This process takes about 15 to 60 minutes, depending on the volume

Consent for publication All participants included in this study provided written informed consent