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10 Specialist advice or referral should be sought immediately if: 6 The rash is severe, widespread or affecting multiple dermatomes Systemic symptoms are present The patient is severely immunocompromised, e.g

Heilfort L, Kutschan S, Drfler J, Freuding M, Bntzel J, Mnstedt K, et al

Note that the cytoprotection concept, as originated by Robert [16,17] and Szabo [18,19,20,21], is commonly regarded as a breakthrough in gastroenterology [22,23,24,25,26]

This homeostatic mechanism has been a key focus in wound healing and dermatological research models

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