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The published research literature has investigated: Gene expression modulation across hundreds of genes (documented in microarray studies) Collagen synthesis and skin remodeling Tissue protection through antioxidant and copper-dependent mechanisms Wound healing and dermatological research Various aging-related cellular processes The mechanisms don't overlap meaningfully

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[38,39] Geroprotective effect of Metformin has been reported in multiple animal models including lifespan extension in Caenorhabditis elegans , Drosophila melanogaster and mice, and deceleration of aging clocks in male nonhuman primates

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Conflict of interest Authors NR-S, HR, and EN were employed by VTT Technical Research Centre of Finland Ltd

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Lactic acid bacteria and their bacteriocins: classification, biosynthesis and applications against uropathogens: a mini-review

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[DOI] [PMC free article] [PubMed] [Google Scholar] 200.Atila F., Tuzel Y., Fernndez J.A., Cano A.F., Sen F

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There is no consensus regarding oral or intravenous supplementation (397)

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