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If the GLP-1/GIP/glucagon receptor class shows disease-modifying behaviour in OA rather than just mechanical pain relief from weight loss, it expands the scientific rationale for the compound and reinforces the argument that the triple-agonist mechanism is doing more than suppressing appetite

As a subcutaneously injected peptide, its bioavailability is not affected by food intake at the time of injection

doi: 10.1089/ten.2004.10.1148

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