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The required NAPDH for the action of GSH reductases, peroxideroxins, and Gpxs is mainly supplied by the pentoze phosphate pathway [204]

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It was investigated as a candidate obesity therapeutic but did not meet its primary endpoints in clinical trials, and no marketing approval followed

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274,275 In addition, ginsenosides have been shown in laboratory and animal studies to reduce vascular inflammation and stiffness, stabilize atherosclerotic plaques, and slow atherosclerosis progression, which may help prevent thromboembolism