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It binds to the GHS-R1a receptor, which triggers a GH pulse through a different signaling cascade

Olsen NJ, Teal GP, Brooks RH: IgM-rheumatoid factor and responses to second-line drugs in rheumatoid arthritis

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[161] reported that the rapalog, RAD001, improved immune functions in elderly people, e.g., it enhanced the response to influenza vaccination

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