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Moreover, most of cell-cycle genes involved in G2-M or G1-S transitions contains E-box regulatory elements in their promoters, transcriptionally activated by CLOCK:BMAL1 heterodimer 29

& Hur, S

2006 Oct;43(5):306-11

Causes of photooxidative stress and amelioration of defense systems in plants

Due to this high aerobic demand, the generation of high amounts of ROS and other oxidative by-products is unavoidable ( GSH is synthesized via two ATP-dependent enzymatic steps catalyzed by glutamate-cysteine ligase (GCL) and glutathione synthetase

Almost 100% of the adult population in the world is infected with at least one HHV during their life 256