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The Cystine/Glutamate antiporter, SLC7A11/xCT, mediates the uptake of extracellular cystine, which is reduced to cysteine, the precursor for glutathione synthesis, protecting cells from oxidative stress [6]

As an important intracellular antioxidant, it acts as a regulator of cellular redox state protecting cells from damage caused by lipid peroxides, reactive oxygen and nitrogen species, and xenobiotics

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Sorafenib, rapamycin, and venetoclax attenuate doxorubicin-induced senescence and promote apoptosis in HCT116 cells

Abstract Epidermal growth factor receptor (EGFR)-mediated cell signaling is critical for mammary epithelial cell growth and survival