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Cellular GSH Homeostasis Glutathione, a tripeptide composed of glutamate, cysteine and glycine, is an antioxidant molecule ubiquitous in most living organisms

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Importantly, ( R )-dHTC1 did not impact either cell line and KO of CRBN conferred resistance to ( S )-dHTC1 in MV4;11 cells, demonstrating on-target antiproliferative activity (Fig

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