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In the cytoplasm, ATOX1 binds Cu(I) and delivers it to one of the copper-dependent ATPases, ATP7A (ATPase copper transporting alpha) and ATP7B (ATPase copper transporting beta), in the Golgi network [47]

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We began to observe the accumulation of ferroptotic cells, as detected upon the intercalation of a cell-impermeable fluorescent dye within nuclear DNA, following 24 h of cystine deprivation (Supplementary Fig