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Insights into the molecular mechanisms of methylmalonic acidemia using microarray technology

The study also did not assess cross reactivity of statins, and statin rechallenge was only described in one case, the authors did not report whether the patient was in the hepatocellular or cholestatic liver injury cohort

Representative LC-MS chromatograms of serum and urine samples displayed marked differences in lipid profiles between RA and OA/HC ( Figures 2A, B )

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in 2022 involving 3,304 PCS patients in which a subset of individuals showed a plethora of symptoms including headaches (27.8%), fatigue (26.7%), muscle pain (23.14%), loss of smell (22.8%), altered taste (12.1%), sleep disturbances (63.1%), confusion (32.6%), focus impairment (22%), symptoms resembling PTSD (31%), feelings of depression (20%), and even thoughts of self-harm (2%) [116]

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