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doi: 10.1016/j.niox.2019.02.001 150 HedlundPAszdiAPfeiferAAlmPHofmannFAhmadMet al

Li, J., et al

Sudano Roccaro A, Blanco AR, Giuliano F, Rusciano D, Enea V: Epigallocatechin-gallate enhances the activity of tetracycline in staphylococci by inhibiting its efflux from bacterial cells

Therefore, depletion of NADPH stores in G6PD-d has the potential to both limit the production of ROS by NOX family enzymes, while simultaneously expediting the accumulation of ROS from non-NADPH-dependent sources, such as the mitochondrial electron transport chain, peroxisomal -oxidation, oxidative protein folding, and other cytoplasmic enzymes (xanthine oxidase, cyclooxygenase, lipoxygenase) 95,96

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Glassford, 2017