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This hypothesis is strengthened by studies where the experimental administration of anti-angiogenic agents in mice from different obesity models resulted in significant weight reduction and adipose tissue loss (222)

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Determining the optimal dose-response curve is a critical part of the research

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In a seminal study in diet-induced obese mice, 5-amino-1MQ administration led to a 35% reduction in mass and size, a 30% decrease in adipocyte size, and a 40% decrease in adipocyte volume in the rodents