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Amyloid beta fragments responsible for the pathological conditions in AD AD patients have insoluble peptides known as amyloid beta due to the digestion of APP by alpha- and gamma-secretases, leading to amyloid beta plaques and cell degeneration

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Free Radical Biol Med 31(10):12791283 Dungel P, Mittermayr R, Haindl S, Osipov A, Wagner C, Redl H et al (2008) Illumination with blue light reactivates respiratory activity of mitochondria inhibited by nitric oxide, but not by glycerol trinitrate