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Several studies have shown that specific promoters of genes, related to neural plasticity and learning and memory, could be modified by neuronal activity through methylation and demethylation [70]
Shahid S, Khan A, Shahid W, Rehan M, Asif R, Nisar H, et al
Clarke C, Korphaisarn K, Jiang Z, Crosby S, Davis DW, Wu W, Raghav KPS, Overman MJ, Morris VK, Kee BK, Eng C, Fogelman DR, Navin N, Kopetz S

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ASO-based PKM splice-switching therapy inhibits hepatocellular carcinoma growth
