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We find that although HGF/c-MET-targeted therapy has led to breakthroughs in certain cancers, monotherapy of targeting HGF/c-MET has failed to demonstrate significant clinical efficacy in most cancers

Most studies report that in humans, NCs disappear when they are about 710 years of age, whereas the age of onset of disc degeneration is 3050 years [8]
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In some cells, the enzyme telomerase lengthens the telomeres [1, 4]

Cancer Res 66:37373746 Valis K, Prochazka L, Boura E, Chladova J, Obsil T, Rohlena J, Truksa J, Dong LF, Ralph SJ, Neuzil J (2011) Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner
