b12 levels after injection High in Blood: What It Really Means · PA Relief Vitamin B12 | The BMJ

Altered B12 handling and reduced clearance in kidney disease, and both cellular release and reduced clearance in liver disease, can raise B12, so supportive renal or hepatic findings make those causes plausible

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PMCID: PMC9249349

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For researchers designing comparative protocols, administration route is not an equivalent variable between the two compounds