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Both vitamin B12 deficiency and folate deficiency are more common in older people, affecting around 1 in 10 people aged 75 or over and 1 in 20 people aged 65 to 74

The following is the typical dosing schedule for weeks 5-16: Weeks 5-8: 0.5 mg (semaglutide) / 0.5 mcg (vitamin B12) once weekly Weeks 9-12: 1.0 mg (semaglutide) / 0.5 mcg (Vitamin B12) once weekly Weeks 13-16: 1.7 mg (semaglutide) / 0.5 mcg (Vitamin B12) once weekly Weeks 17 onwards: 2.5 mg (semaglutide) / 0.5 mcg (Vitamin B12) once weekly, if further weight loss is required