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Ethnicity imposes greater risk for development of neuropathy following vincristine, which is metabolized via the cytochrome P450 (CYP) 3A4 and CYP3A5 pathways (Dennison et al., 2007)

& Rosmalen, J

[DOI] [PubMed] [Google Scholar] 5.Cruzat V., Macedo Rogero M., Noel Keane K., Curi R., Newsholme P

10.1371/journal.pone.0095935 [DOI] [PMC free article] [PubMed] [Google Scholar] 213.Uppal N, Uppal V, Uppal P

THC, CBD, and CBN are also capable of inhibiting CYP2D6, with CBD being the most potent competitive inhibitor

Seeds explores the intricate cellular pathways behind a number of neurodegenerative diseases, isolating the mechanistic issues that can set off neuronal degradation