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Three methods of opioid detoxification in a primary care setting: A randomized trial

The scientific answer remains no
et al., 2006

It is almost always paired with ipamorelin

Antonoff MB , Ragalie W, Correa AM, Spicer JD, Sepesi B, Roth JA, Walsh GL, Hofstetter WL, Swisher SG, Rice DC, Vaporciyan AA, Mehran RJ

Opioid pathways activation mediates the activity of nicorandil in experimental models of nociceptive and inflammatory pain
