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L-asparaginase: therapeutic and toxic effects in patients with neoplastic disease

Nerve pain is usually perceived as burning, electric, shock-like, tingling or sharp and may start at one location and shoot, or radiate to another location (like sciatica)
In July 2025, Takeda reported positive Phase III results for oveporexton (TAK-861) in NT1, meeting all efficacy endpoints with robust symptom improvement and good tolerability
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