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Who may need high dosages of B12: People with absorption difficulties due to insufficient stomach acid, lack of intrinsic factor (pernicious anemia), or gastrointestinal surgery 6 Vegans/strict vegetarians People affected by certain genetic variants, e.g

Reduction of ScGrx7 by GSH is slower than the oxidation by GSSCys (unless Lys105 is replaced, which decelerates the oxidative half-reaction even more than the reductive half-reaction owing to the dual activator function)

Medical researchers from Italy treated adults with either alcoholic or nonalcoholic fatty liver disease with an IV drip filled with high doses of GSH

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