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187 Human UC-MSCs primed with IFN--Exos reduce oxidative stress and inflammatory responses in mice, 188 and MSC-Exos reverse ALI through the nuclear factor NF-E2-related factor 2 (Nrf-2)/antioxidant response element (ARE) and NF-B signaling pathways

Gpx activity in the liver of WT mice also was increased by Con A injection, and it was decreased in the liver of both saline- and Con A-injected Gpx1 KO mice (Figure 1b)

From a hostpathogen interaction perspective, PQS modulates host inflammation 7 , cellular function 8 , and exhibits direct cytotoxic effects, leading to host cell death through various modalities

Senf SM

D., Ayala, G

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