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The computed energy barrier for Cu(II)-catalyzed methionine oxidation is 14.3 kcal/mol significantly lower than for Zn (19.6 kcal/mol) or Fe (16.9 kcal/mol), making copper the most efficient catalyst among common metal ions

The American Peptide Society summarized these concerns bluntly, noting that limited detail and missing sequence information make the original work difficult to reproduce (American Peptide Society)

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Prolonged DNA insults eventually lead to disruption of signaling pathways that control cellular growth in lung tissue

Integrative interventions like vitamin D, melatonin, and soy isoflavones have been shown in studies to affect survival rates in lung cancer patients

[PubMed] [Google Scholar][82] Horio N, Horiguchi M