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pp 13891399 Marin DB, Davis K
Matrix involvement results in pitting, leukonychia, nail plate thickening or thinning, onychorrhexis, and crumbling (Fig
doi: 10.1093/ajcn/54.4.712
Treatment may be discontinued in patients who do not achieve an early virological response at 12 weeks, although the decision should be individualized according to the tolerability of therapy, severity of underlying liver disease and demonstration of some degree of biochemical and/or virological response (I, III) 14
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