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Interestingly, the weight loss effect of AOD-9604 did not follow the usual "more is better" principle
Lechner MC
Interestingly, this was not correlated with significant changes in pyruvate and glucose consumption, or glutamine consumption, suggesting the resistant cells were taking up oxidizable substrates for the TCA cycle from other sources such as amino acids or fatty acids (Farge et al., 2017)
Maitz, Peter K
