n-acetylcysteine glutathione precursor heavy metal detox N-acetylcysteine: A Review of Clinical Use and Efficacy N-Acetylcysteine (NAC) 500 mg |

And why do I say that

The linkage between altered catalase expression and an array of disorders has been substantiated by findings indicating specific mutations in the catalase gene correlating with diminished catalase activity, with such associations being documented in the context of diabetes, hypertension, vitiligo, Alzheimers disease, and acatalasemia [48,49]

Sastre et al

H.KrugerM

Whole-muscle cross-sectional area (CSA) and IGF-I mRNA expression was highly correlated in the chronic heart failure group, with no significant correlation detected in the control group

The above insights are being tested in a clinical trial (NCT04107311) that aims to prospectively investigate the role of the intestinal microbiome and autoimmune panels as predictors of Grade 2 irAEs requiring immunosuppression