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Monitor side effects and modify with a doctor to optimize benefits and reduce risks

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Nishioka S, Takayama M, Watanabe M, Urusihara M, Kiriya Y, Hijioka S

PLC 1a is longer and contains a consensus postsynaptic density protein/ Drosophila disc large tumor suppressor/zona occludens-1 protein motif at its C terminus, whereas PLC 1b contains a proline-rich region (Bahk et al., 1994, 1998

In addition, peroxisomal fat oxidation is required for the biosynthesis of ascaroside pheromones, which are signaling molecules that control dauer formation, lifespan, and behavior in this model animal (Park and Paik, 2017)

Summary: Berberine and L-carnitine can be taken together as no direct interactions are documented, but evidence for their combined use is limited and neither is recommended in UK clinical guidelines