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By preserving NAD+ and SAM in both fat and muscle tissue, NNMT inhibition may theoretically address the metabolic dysfunction underlying both excessive fat storage and impaired muscle maintenance

No hormone-related therapy should be considered automatically safer without a proper medical evaluation

The injection frequency is low enough that the marginal comfort difference does not matter as much

The folate cycle is crucial for its role in the synthesis of S-adenosylmethionine (SAM) and the metabolism of vitamin B12 (, , , )

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