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In Vitro Reconstitution of Functional Small Ribosomal Subunit Assembly for Comprehensive Analysis of Ribosomal Elements in E

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Mahmoud SS, et al

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While similar amounts of U1-A and CPSF-160 were co-immunoprecipitated with FUS/TLS for both wild-type and each mutant, the association of U1-70K and Sm-B/D (components of Sm core) was sharply reduced (by about fivefold) for the cytoplasmically mislocalized R495X and P525L, and the nuclear R521G mutant (Fig

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