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Also, poly (GR) 80 interacts with mitochondrial ribosomal proteins, inducing mitochondrial dysfunction, in motor neurons differentiated from C9orf72 patient iPSCs, compared to controls (Lopez-Gonzalez et al., 2016)

However, it is worth emphasizing that, although plasma glutamine concentration is reduced from its normal concentration (i.e., 500800 mol/L) to 300400 mol/L, cells depending on this amino acid, such as immune cells, are in fact poorly influenced in terms of proliferation and function [6]

10.4161/15548627.2014.973737 48 Di MauroV.IafiscoM.SalvaraniN.VacchianoM.CarulloP.Ramrez-RodrguezG