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The antioxidant response genes activated by NRF2 include genes responsible for (a) regulating GSH synthesis and metabolism, (b) antioxidant proteins like GPX, (c) drug-metabolizing enzymes and xenobiotic transporters, and (d) additional stress response proteins (Jaramillo and Zhang, 2013)

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Oncotarget 8 (30), 4933849350

Eukaryot Cell 1:391400 Sohn MJ, Yoo SJ, Oh DB, Kwon O, Lee SY, Sibirny AA, Kang HA (2014) Novel cysteine-centered sulfur metabolic pathway in the thermotolerant methylotrophic yeast Hansenula polymorpha

Effect of human plasma exosomes on U1 monocytic cells We previously reported that ALC-induced CYP2E1 expression in monocytic/macrophage cell lines resulted in increased oxidative stress and cytotoxicity 8

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